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[Antiviral activity of aqueous extracts of the birch fungus Inonotus obliquus on the human immunodeficiency virus].

Authors
  • Shibnev, V A
  • Garaev, T M
  • Finogenova, M P
  • Kalnina, L B
  • Nosik, D N
Type
Published Article
Journal
Voprosy virusologii
Publication Date
Jan 01, 2015
Volume
60
Issue
2
Pages
35–38
Identifiers
PMID: 26182655
Source
Medline
License
Unknown

Abstract

Fractions of aqueous and water-alcohol extracts of the birch fungus Inonotus obliquus have antiviral effect against the human immunodeficiency virus type 1 (HIV-1). Antiviral properties of low toxic extracts were manifested in the concentration of 5.0 μg/ml upon simultaneous application with the virus in the lymphoblastoid cells culture MT-4. The extract of the birch fungus can be used for development of new antiviral drugs, inhibitors of HIV-replication when used both in the form of individual drugs and as a part of complex therapy.

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