Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion.

Daniel Chappell; Matthias Jacob; Klaus Hofmann-Kiefer; Markus Rehm; Ulrich Welsch; Peter Conzen; Bernhard F Becker

doi:10.1093/cvr/cvp097

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Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion.

Authors

Chappell, Daniel
Jacob, Matthias
Hofmann-Kiefer, Klaus
Rehm, Markus
Welsch, Ulrich
Conzen, Peter
Becker, Bernhard F

Type

Published Article

Journal

Cardiovascular Research

Publisher

Oxford University Press

Publication Date

Jul 15, 2009

Volume

83

Issue

2

Pages

388–396

Identifiers

DOI: 10.1093/cvr/cvp097

PMID: 19307232

Source

Medline

License

Unknown

Abstract

Antithrombin preserves the endothelial glycocalyx, sustaining the vascular barrier function and reducing interstitial oedema. The potentiated effect of colloid in these hearts suggests that the prevention of shedding should be of functional benefit also in vivo.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. This record was last updated on 07/04/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM. The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/19307232

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