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Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm.

Authors
  • Maust, Donovan T1
  • Kim, Hyungjin Myra2
  • Seyfried, Lisa S3
  • Chiang, Claire1
  • Kavanagh, Janet3
  • Schneider, Lon S4
  • Kales, Helen C1
  • 1 Department of Psychiatry, University of Michigan, Ann Arbor2Center for Clinical Management Research, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan.
  • 2 Center for Clinical Management Research, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan3Center for Statistical Consultation and Research, University of Michigan, Ann Arbor.
  • 3 Department of Psychiatry, University of Michigan, Ann Arbor.
  • 4 Department of Psychiatry, University of Southern California, Los Angeles.
Type
Published Article
Journal
JAMA Psychiatry
Publisher
American Medical Association
Publication Date
May 01, 2015
Volume
72
Issue
5
Pages
438–445
Identifiers
DOI: 10.1001/jamapsychiatry.2014.3018
PMID: 25786075
Source
Medline
License
Unknown

Abstract

The absolute effect of antipsychotics on mortality in elderly patients with dementia may be higher than previously reported and increases with dose.

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