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Antinociceptive activity of a hydroalcoholic extract obtained from aerial parts of Sebastiania schottiana (Euphorbiaceae).

Authors
  • Luzzi, R
  • Scheidt, C
  • Roos, J F
  • Cechinel Filho, V
  • Santos, A R
  • Calixto, J B
  • Yunes, R A
  • Niero, R
Type
Published Article
Journal
Die Pharmazie
Publication Date
Sep 01, 2000
Volume
55
Issue
9
Pages
681–683
Identifiers
PMID: 11031773
Source
Medline
License
Unknown

Abstract

This study analyzed the antinociceptive effects of a hydroalcoholic extract obtained from the aerial parts of Sebastiania schottiana, a Brazilian medicinal plant used to treat various painful diseases. For this purpose, the writhing test, capsaicin and formalin induced-pain in mice were used. The results showed that the hydroalcoholic extract exhibited considerable antinociception in all the models studied, being more potent than aspirin.

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