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[Antimutagenic action of superoxide dismutase on sodium azide- and nitrosoguanidine-induced mutagenesis in Salmonella typhimurium TA 1535].

Authors
Type
Published Article
Journal
Genetika
Publication Date
Volume
29
Issue
5
Pages
760–767
Identifiers
PMID: 8392962
Source
Medline

Abstract

It was shown that superoxide dismutase (SOD) decreased the mutagenic action of sodium azide (NaN3) and N-methyl-N'-nitro-N-nitrosoguanidine in Salmonella typhimurium TA1535. Catalase and quenchers of hydroxyl radicals showed, unlike SOD no effect on the mutagenicity of NaN3. Cell extract from propionic acid bacteria also possessed the antimutagenic activity, only partially depending on the SOD activity.

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