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Antimicrobial potential of two different Hypericum species available in India.

Authors
  • Mukherjee, Pulok K
  • Saritha, G S
  • Suresh, B
Type
Published Article
Journal
Phytotherapy research : PTR
Publication Date
Nov 01, 2002
Volume
16
Issue
7
Pages
692–695
Identifiers
PMID: 12410558
Source
Medline
License
Unknown

Abstract

The antimicrobial activity of extracts of the leaves and stems of two different varieties of Hypericum was evaluated by the disc diffusion method. Petroleum ether, acetone, chloroform and methanol extracts of Hypericum mysorense and Hypericum patulum stems and leaves were investigated for their antimicrobial activity against six different strains of bacteria and fungi by the zone of inhibition method (ZIM). The results showed that both the stem and leaf extracts of both species have a very broad spectrum of antibacterial activity. The petroleum ether and acetone extract of the leaves and stems of H. mysorense did not show antifungal effects against any of the six fungal organisms tested but other extracts showed a potential antifungal effect which was comparable to that of griseofulvin, the standard antifungal agent. Thus these results demonstrate that the leaf and stem extracts of both the Hypericum species have a very broad spectrum of activity and suggest that they may be useful in the treatment of various microbial infections.

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