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Antimicrobial peptides.

Authors
Type
Published Article
Journal
Upsala journal of medical sciences
Publication Date
Volume
119
Issue
2
Pages
199–204
Identifiers
DOI: 10.3109/03009734.2014.899278
PMID: 24758244
Source
Medline
Keywords
License
Unknown

Abstract

With increasing antibiotics resistance, there is an urgent need for novel infection therapeutics. Since antimicrobial peptides provide opportunities for this, identification and optimization of such peptides have attracted much interest during recent years. Here, a brief overview of antimicrobial peptides is provided, with focus placed on how selected hydrophobic modifications of antimicrobial peptides can be employed to combat also more demanding pathogens, including multi-resistant strains, without conferring unacceptable toxicity.

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