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Anti-Irritant and Anti-Inflammatory Effects of DHA Encapsulated in Resveratrol-Based Solid Lipid Nanoparticles in Human Keratinocytes

Authors
  • serini, simona
  • cassano, roberta
  • facchinetti, enrica
  • amendola, gaia
  • trombino, sonia
  • calviello, gabriella
Publication Date
Jun 21, 2019
Source
MDPI
Keywords
Language
English
License
Green
External links

Abstract

, IL-6, and 1 MCP-1, in the two keratinocyte cell lines, as well as the NLRP3 inflammasome activation. Moreover, it more efficiently reduced the upsurge of reactive oxygen species (ROS) levels obtained in the presence of a pro-oxidant (H2O2). Overall, our findings suggest the possibility that a sustained dietary supplementation with DHA-RV-SLNs could efficiently protect skin from the pro-irritant and pro-inflammatory activity of environmental attacks.

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