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Anti-inflammatory Potential of Terpenes Present in Cannabis sativa L.

Authors
  • Downer, Eric J1
  • 1 Discipline of Physiology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, University of Dublin, Dublin, Ireland. , (Ireland)
Type
Published Article
Journal
ACS Chemical Neuroscience
Publisher
American Chemical Society
Publication Date
Mar 04, 2020
Volume
11
Issue
5
Pages
659–662
Identifiers
DOI: 10.1021/acschemneuro.0c00075
PMID: 32091871
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Cannabis sativa L. (C. sativa) contains an array of plant-derived (phyto) cannabinoids and terpenes that are predominantly located in the trichome cavity of the plant. Terpenes, aromatic organic hydrocarbons characterized for their role in plant protection/pollination, are gaining attention for their potential as novel therapeutics in many areas of biomedicine. This Viewpoint will explore the exciting recent evidence that terpenes have anti-inflammatory/antioxidant propensity by targeting inflammatory signaling mechanisms relevant to human disease. Given their anti-inflammatory properties, terpenes may contribute to the effects of current cannabinoid-based therapies.

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