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Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2.

Authors
  • Foureaux, Giselle
  • Nogueira, José C
  • Nogueira, Bárbara S
  • Fulgêncio, Gustavo O
  • Menezes, Gustavo B
  • Fernandes, Simone O A
  • Cardoso, Valbert N
  • Fernandes, Renata S
  • Oliveira, Gabriel P
  • Franca, Juçara R
  • Faraco, André A G
  • Raizada, Mohan K
  • Ferreira, Anderson J
Type
Published Article
Journal
Investigative Ophthalmology & Visual Science
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Publication Date
Jun 01, 2013
Volume
54
Issue
6
Pages
4296–4306
Identifiers
DOI: 10.1167/iovs.12-11427
PMID: 23702784
Source
Medline
Keywords
License
Unknown

Abstract

Our results evidence the pathophysiologic relevance of the ocular ACE2/Ang-(1-7)/Mas axis of the renin-angiotensin system and, importantly, indicate that the activation of intrinsic ACE2 is a potential therapeutic strategy to treat glaucoma.

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