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Antigenic mimicry of mammalian intermediate filaments by mycoplasmas.

Authors
  • Wise, K S
  • Watson, R K
Type
Published Article
Journal
Infection and immunity
Publication Date
May 01, 1985
Volume
48
Issue
2
Pages
587–591
Identifiers
PMID: 2580796
Source
Medline
License
Unknown

Abstract

A murine monoclonal antibody raised against Mycoplasma hyorhinis specifically reacted by indirect immunofluorescence with mammalian intermediate filaments. The antibody recognized a related epitope on a 74,000-molecular-weight protein of M. hyorhinis and on components of similar size from other pathogenic mycoplasmas. This defines a shared antigenic structure of interest in autoantibody development during mycoplasmal diseases.

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