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An antifungal constituent from the stem bark of Butea monosperma.

Authors
  • Bandara, B M1
  • Kumar, N S
  • Samaranayake, K M
  • 1 Department of Chemistry, University of Peradeniya, Sri Lanka. , (Sri Lanka)
Type
Published Article
Journal
Journal of Ethnopharmacology
Publisher
Elsevier
Publication Date
Feb 01, 1989
Volume
25
Issue
1
Pages
73–75
Identifiers
PMID: 2716344
Source
Medline
License
Unknown

Abstract

The petroleum and ethyl acetate extracts of the stem bark from Butea monosperma displayed antifungal activity against Cladosporium cladosporioides. The active constituent of low polarity was isolated by bioassay-monitored chromatographic fractionation, and identified as (-)-medicarpin by comparison of physical data. The antifungal activity of (-)-medicarpin was found to be greater than that of Benlate, a standard fungicide, while (-)-medicarpin acetate also exhibited significant activity against C. cladosporiodes.

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