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Anticancer effects of human amniotic membrane and its epithelial cells

Authors
  • Niknejad, Hassan
  • Yazdanpanah, Ghasem1, 2, 3, 4, 3
  • 1 Department of Tissue Engineering
  • 2 School of Advanced Technologies in Medicine
  • 3 Shahid Beheshti University of Medical Sciences
  • 4 Nanomedicine and Tissue Engineering Research Center
Type
Published Article
Journal
Medical Hypotheses
Publisher
Elsevier
Publication Date
Jan 01, 2014
Accepted Date
Jan 31, 2014
Volume
82
Issue
4
Pages
488–489
Identifiers
DOI: 10.1016/j.mehy.2014.01.034
Source
Elsevier
License
Unknown

Abstract

Anticancer property of the amniotic membrane, the innermost layer of fetal membrane, was previously hypothesized. The recent reports confirmed the published hypotheses and developed new hypotheses in this context. Based on some evidences, it is hypothesized that inducing of apoptosis in cancer cells is originated from amniotic epithelial cells and cancer cell cycle arrest arises from amniotic mesenchymal cells. We also hypothesized here that apoptosis and cell cycle arrest in cancer cells induced by amniotic membrane arise from release of soluble factors from amniotic cells.

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