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Anticancer activities of constituents from the stem of Polyalthia rumphii.

Authors
  • Wang, Tianshan
  • Yuan, Yuan
  • Wang, Jing
  • Han, Changri
  • Chen, Guangying
Type
Published Article
Journal
Pakistan journal of pharmaceutical sciences
Publication Date
Apr 01, 2012
Volume
25
Issue
2
Pages
353–356
Identifiers
PMID: 22459461
Source
Medline
License
Unknown

Abstract

Nine known compounds were firstly isolated from the chloroform extract of Polyalthia rumphii stem by anticancer activity guidance, and the chemical structures were identified by using spectroscopic and physico-chemical analysis. Cytotoxic evaluation against four cancer cell lines was performed on all these compounds, which showed that K562 could be significantly inhibited by partial compounds with IC(50) values at the range from 40 to 60 μ/mL.

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