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Antibody to hepatitis C virus in blood donors found positive for other agents. I. Treponemal infection.

Authors
  • Aloysius, S
  • Howell, D R
  • Barbara, J A
Type
Published Article
Journal
Transfusion medicine (Oxford, England)
Publication Date
Sep 01, 1991
Volume
1
Issue
3
Pages
191–193
Identifiers
PMID: 9259848
Source
Medline
License
Unknown

Abstract

Stored serum samples from 169 blood donors found positive for TPHA were tested for antibodies to hepatitis C virus (anti-HCV) and to hepatitis B core (anti-HBc), as evidence of previous HBV infection, a condition known to be sexually transmissible. Only three donors were positive with a 'first generation' anti-HCV and all three failed to confirm with a recombinant immunoblot assay (RIBA). In contrast, 33 (19.5%) of the TPHA-positive donors were positive for anti-HBc. The results suggest that sexual transmission is not a major factor in the spread of HCV.

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