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Antiatherosclerotic effects of long-term maximally intensive statin therapy after acute coronary syndrome: insights from Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin Versus Atorvastatin.

Authors
  • Puri, Rishi
  • Nissen, Steven E
  • Shao, Mingyuan
  • Ballantyne, Christie M
  • Barter, Philip J
  • Chapman, M John
  • Erbel, Raimund
  • Libby, Peter
  • Raichlen, Joel S
  • Uno, Kiyoko
  • Kataoka, Yu
  • Nicholls, Stephen J
Type
Published Article
Journal
Arteriosclerosis Thrombosis and Vascular Biology
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Nov 01, 2014
Volume
34
Issue
11
Pages
2465–2472
Identifiers
DOI: 10.1161/ATVBAHA.114.303932
PMID: 25212234
Source
Medline
Keywords
License
Unknown

Abstract

Long-term high-intensity statin therapy caused greater plaque regression and comparable major adverse cardiovascular events rates in ACS when compared with non-ACS patients. Despite a higher clinical risk profile, patients with ACS harbor a more modifiable disease substrate and seem to benefit the most from potent statin therapy.

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