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Anti-arrhythmic Drugs—a Review and Comment on Relevance in the Current Era: Part 1

Authors
  • Hanayneh, Seri1, 2
  • Panna, Mark E.1, 2
  • Miles, William M.1, 2
  • Goel, Ramil1, 2
  • 1 University of Florida, 1600 SW Archer Rd, Gainesville, FL, 32608, USA , Gainesville (United States)
  • 2 VA Medical Center – North Florida/South Georgia, 1601 SW Archer Rd, Gainesville, FL, 32608, USA , Gainesville (United States)
Type
Published Article
Journal
Current Treatment Options in Cardiovascular Medicine
Publisher
Springer US
Publication Date
Jul 21, 2021
Volume
23
Issue
9
Identifiers
DOI: 10.1007/s11936-021-00940-3
Source
Springer Nature
Keywords
Disciplines
  • Topical Collection on Arrhythmia
License
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Abstract

Purpose of reviewThere is apprehension and a general lack of familiarity with regard to using the ionic channel specific anti-arrhythmic agents among internists and even general cardiologists.Recent findingsThis may be related to their relative infrequent use, complicated mechanisms of actions, and real or perceived risks involved with their use. For example, the fact that coronary artery disease is listed as contraindication to the prescription of class IC agents, when so many patients are noted to have presence of non-obstructive disease on increasingly done CT scans, causes confusion and uncertainty about their use.SummaryThis review paper will attempt to lay out the general pharmacology of the commonly used anti-arrhythmic drugs and discuss their relevance and safe use in current clinical medicine.

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