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Antiangiogenic therapy for primary liver cancer: correlation of changes in dynamic contrast-enhanced magnetic resonance imaging with tissue hypoxia markers and clinical response.

Authors
  • Yopp, Adam C
  • Schwartz, Lawrence H
  • Kemeny, Nancy
  • Gultekin, David H
  • Gönen, Mithat
  • Bamboat, Zubin
  • Shia, Jinru
  • Haviland, Dana
  • D'Angelica, Michael I
  • Fong, Yuman
  • DeMatteo, Ronald P
  • Allen, Peter J
  • Jarnagin, William R
Type
Published Article
Journal
Annals of Surgical Oncology
Publisher
Springer - Society of Surgical Oncology
Publication Date
Aug 01, 2011
Volume
18
Issue
8
Pages
2192–2199
Identifiers
DOI: 10.1245/s10434-011-1570-1
PMID: 21286939
Source
Medline
License
Unknown

Abstract

In patients with PLC, bevacizumab induces a reduction in tumor perfusion measured by DCE-MRI. These changes correlate with TTP and tissue markers of tumor hypoxia.

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