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Antiangiogenic effect of sulindac sulfide could be secondary to induction of apoptosis and cell cycle arrest.

Authors
  • Flis, S
  • Soltysiak-Pawluczuk, D
  • Jedrych, A
  • Jastrzebski, Z
  • Remiszewska, M
  • Splawinski, J
Type
Published Article
Journal
Anticancer research
Publication Date
Jan 01, 2006
Volume
26
Issue
4B
Pages
3033–3041
Identifiers
PMID: 16886631
Source
Medline
License
Unknown

Abstract

The results suggest that the anti-angiogenic activity of sulindac sulfide is secondary to the inhibition of endothelial cell survival resulting from cell cycle arrest and apoptosis.

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