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Anti-oral microbial activity of isoflavonoids in root bark of Ormosia monosperma.

Authors
  • Iinuma, M
  • Okawa, Y
  • Tanaka, T
  • Ho, F C
  • Kobayashi, Y
  • Miyauchi, K I
Type
Published Article
Journal
Phytochemistry
Publisher
Elsevier
Publication Date
Oct 01, 1994
Volume
37
Issue
3
Pages
889–891
Identifiers
PMID: 7765696
Source
Medline
License
Unknown

Abstract

From the root bark of Ormosia monosperma, 10 isoflavonoids including two new compounds 7,4'-dihydroxy-6",6"-dimethylpyrano-(2",3":5,6)-8-(3-methyl-1,3- butadienyl)isoflavone, named ormosidin, and dalbergion 4'-O-beta-D-glucopyranoside, were isolated. These structures were confirmed by spectroscopic analysis. 2,3-Dihydroauriculatin, one of the compounds isolated, showed moderate activities against oral-microbial organisms (Streptococcus mutans, Prophyromonas gingivalis and Actinomyces actinomycetemcomitans).

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