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Anti-CD25 monoclonal antibody therapy affects the death signals of graft-infiltrating cells after clinical heart transplantation.

Authors
  • Baan, C C
  • Balk, A H M M
  • van Riemsdijk, I C
  • Vantrimpont, P J M J
  • Maat, A P W M
  • Niesters, H G M
  • Zondervan, P E
  • van Gelder, T
  • Weimar, W
Type
Published Article
Journal
Transplantation Journal
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
May 26, 2003
Volume
75
Issue
10
Pages
1704–1710
Identifiers
PMID: 12777860
Source
Medline
License
Unknown

Abstract

Our data suggest that immunosuppressive agents that affect the IL-2 pathway hinder the mechanism of activation-induced cell death by which the immune system eliminates alloreactive cells.

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