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Anti-CCP antibodies in Brazilian children and adults with juvenile idiopathic arthritis

Authors
  • Bacos, S.1
  • Bortolozzi, S. G.1
  • Skare, T. S.1
  • Spelling, P. F.1
  • Utiyama, S. R. R.2
  • Nisihara, R.2, 3,
  • 1 Evangelical University, Rheumatology Unit, Curitiba, Paraná, Brazil , Curitiba (Brazil)
  • 2 Federal University of Paraná, Immunopathology Laboratory, Clinical Hospital, Curitiba, Paraná, Brazil , Curitiba (Brazil)
  • 3 Positivo University, Department of Medicine, Curitiba, Paraná, Brazil , Curitiba (Brazil)
Type
Published Article
Journal
Clinical Rheumatology
Publisher
Springer-Verlag
Publication Date
Mar 21, 2014
Volume
33
Issue
7
Pages
1001–1003
Identifiers
DOI: 10.1007/s10067-014-2578-2
Source
Springer Nature
Keywords
License
Yellow

Abstract

Patients with juvenile idiopathic arthritis (JIA) may need further care in the adult clinic as this disease frequently has continuous inflammatory activity during adult life. To identify which pediatric JIA patients will need continuing care into adulthood. We compared the clinical, serological, and demographic data of 45 JIA patients followed up by the pediatric clinic to those of 49 JIA patients in the adult rheumatology clinic. Patients in the adult clinic have older age at disease onset (p < 0.0001) and higher prevalence of positive anti-cyclic citrullinated peptide (CCP) (p = 0.05). No differences were observed in JIA form, presence of rheumatoid factor (RF), uveitis, and gender. Anti-CCP and older age at disease onset may identify pediatric JIA patients that will need further care in the adult clinic.

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