Annexin A5 uptake in ischemic myocardium: demonstration of reversible phosphatidylserine externalization and feasibility of radionuclide imaging.
- Published Article
- Publication Date
Feb 01, 2010
After a single episode of ischemia, cardiomyocytes express phosphatidylserine, which is amenable to targeting by AA5, for at least 6 h. Phosphatidylserine exposure is transient and internalized in cytoplasmic vesicles after AA5 binding, indicating the reversibility of the apoptotic process.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/20124049