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Anesthetic Management of a Rett Syndrome Patient at High Risk for Respiratory Complications.

Authors
  • Kamekura, Nobuhito1
  • Hojo, Takayuki1
  • Nitta, Yukie1
  • Hase, Yuri1
  • Fujisawa, Toshiaki1
  • 1 Department of Dental Anesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Japan. , (Japan)
Type
Published Article
Journal
Anesthesia progress
Publication Date
Oct 01, 2021
Volume
68
Issue
3
Pages
163–167
Identifiers
DOI: 10.2344/anpr-68-02-07
PMID: 34606569
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Rett syndrome (RTT) is a rare genetic disorder that can present challenges in airway management during general anesthesia. This is a case report involving a 23-year-old woman with RTT who received an intubated general anesthetic 3 times for dental treatment. The patient also had severe scoliosis, was bedridden, and had dysphagia. These contributing factors likely led to the development of postoperative respiratory complications including pneumonia after the first case. As a result, several changes were incorporated into the 2 subsequent anesthetic plans in efforts to reduce the risk of such complications. Despite these measures, the patient was suspected of having bronchitis postoperatively after the second anesthetic, although the third occurred uneventfully. Anesthetic management alterations included use of desflurane for anesthetic maintenance and postoperatively delaying oral intake and instituting active postural changes. © 2021 by the American Dental Society of Anesthesiology.

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