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[Analysis of specificity in the serodiagnosis of acquired immunodeficiency syndrome].

Authors
  • Etkin, A F
  • Pokrovskiĭ, V V
  • Iankina, Z K
Type
Published Article
Journal
Zhurnal mikrobiologii, epidemiologii, i immunobiologii
Publication Date
Sep 01, 1986
Issue
9
Pages
73–76
Identifiers
PMID: 3641508
Source
Medline
License
Unknown

Abstract

Analysis of serum samples for the presence of antibody to AIDS-inducing virus was carried out with the use of the Virognostika diagnosticum manufactured by Organon (the Netherlands). As a result, 6.1% of sera from patients with hematologic diseases, 5.7% of sera from oncologic patients, and 9.2% of sera from hepatitis B patients proved to be "positive" according to the criteria of the manufacturer. However the positively reacting sera could be neutralized by sorption on human red cells, groups AB and 0 and by treatment with the lysate of human lymphocyte culture, which was indicative of the fact that false positive reactions were probably due to the contamination of the antigenic preparation by components of the producer-cell membrane.

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