Analysis of recent trends in prostate cancer incidence and mortality.
- Published Article
- Publication Date
Mar 01, 2000
These data show large increases in early disease, followed by a drop and leveling off along with a decrease in advanced disease (distant stage, 2-year mortality, positive lymph nodes). This indicates that the increasing incidence rates for prostate cancer are largely due to lead-time bias from increased early detection and treatment of prostate cancer. However, since incidence rates have not declined to rates seen in the 1970s, the additional cases may also reflect length bias from insignificant lesions or a true increase in incidence over time.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/10679753