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Analysis of lectin binding sites in the gut of hooded Lister rats with special emphasis on recently detected lectins.

Authors
  • Schumacher, U
  • Madry, H
  • Adam, E
  • Peumans, W J
  • van Damme, E J
  • Grant, G
  • Bardocz, S
  • Pusztai, A
Type
Published Article
Journal
Acta Histochemica
Publisher
Elsevier
Publication Date
May 01, 1993
Volume
94
Issue
2
Pages
163–166
Identifiers
PMID: 8351977
Source
Medline
License
Unknown

Abstract

Seven recently isolated lectins were tested for their ability to bind to tissue sections of rat gut. Binding sites for N-Acetylgalactosamine specific lectins were found in mucins, in the brush border membrane and in goblet cells. Non-reducing terminal mannose residues were absent from cell surface membranes but were detected in the supranuclear region of goblet cells and enterocytes. The results of lectin binding obtained in this study were generally similar to lectin-gut interactions observed in vivo.

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