The angiotensin I-converting enzyme (ACE) contains an insertion/deletion (I/D) polymorphism, with the DD genotype associated with benign renal diseases. The distribution frequencies of the D and I alleles, and the DD, DI and II genotypes were determined in DNA extracted from kidney tissues of 58 renal cancer patients. The observed frequencies in patients who develop renal cancer was not significantly different than the normal population.
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/10682664