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Analysis of the insertion/deletion polymorphism of the human angiotensin converting enzyme (ACE) gene in patients with renal cancer.

Authors
Type
Published Article
Journal
British journal of cancer
Publication Date
Volume
82
Issue
3
Pages
550–552
Identifiers
PMID: 10682664
Source
Medline
License
Unknown

Abstract

The angiotensin I-converting enzyme (ACE) contains an insertion/deletion (I/D) polymorphism, with the DD genotype associated with benign renal diseases. The distribution frequencies of the D and I alleles, and the DD, DI and II genotypes were determined in DNA extracted from kidney tissues of 58 renal cancer patients. The observed frequencies in patients who develop renal cancer was not significantly different than the normal population.

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