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Analysis of Human Breath by Millimeter-Wave/Terahertz Spectroscopy

Authors
  • Rothbart, Nick1
  • Holz, Olaf
  • Koczulla, Rembert2, 3, 4
  • Schmalz, Klaus
  • Hübers, Heinz-Wilhelm1
  • 1 Department of Physics, Humboldt-Universität zu Berlin, 12489 Berlin, Germany
  • 2 Department of Pulmonology, Institute for Internal Medicine, Philipps-University of Marburg, 35043 Marburg, Germany
  • 3 Schön Klinik Berchtesgadener Land, Department for Pulmonology, Teaching Hospital of the Philipps-University, 35043 Marburg, Germany
  • 4 Teaching Department of the Paracelsus University Salzburg, 5020 Salzburg, Austria
Type
Published Article
Journal
Sensors
Publisher
MDPI AG
Publication Date
Jun 17, 2019
Volume
19
Issue
12
Identifiers
DOI: 10.3390/s19122719
PMID: 31212999
PMCID: PMC6630364
Source
PubMed Central
Keywords
License
Green

Abstract

Breath gas analysis is a promising tool for medical research and diagnosis. A particularly powerful technological approach is millimeter-wave/terahertz (mmW/THz) spectroscopy, because it is a very sensitive and highly selective technique. In addition, it offers the potential for compact and affordable sensing systems for wide use. In this work, we demonstrate the capability of a mmW/THz spectrometer for breath analysis. Samples from three volunteers and a sample from ambient air were analyzed with respect to 31 different molecular species. High-resolution absorption spectra were measured by scanning two absorption lines from each species. Out of the 31, a total of 21 species were detected. The results demonstrate the potential of mmW/THz spectroscopy for breath analysis.

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