Affordable Access

An analysis of criteria for biological limit values developed in Germany and in the United States.

Authors
  • Morgan, M S
  • Schaller, K H
Type
Published Article
Journal
International archives of occupational and environmental health
Publication Date
Jul 01, 1999
Volume
72
Issue
4
Pages
195–204
Identifiers
PMID: 10491773
Source
Medline
License
Unknown

Abstract

The biological tolerance values established by the German Research Foundation and the biological exposure indices developed by the American Conference of Governmental Hygienists represent two extensive lists of occupational exposure guidelines for use in biological monitoring. Although there is substantial agreement between the two organizations on most points, there are several important differences in the approaches taken in setting of the guideline values. Analysis of these distinctions serves to focus attention on the current issues impeding international agreement over occupational exposure guidelines. Among these issues are (1) the specification of the biological monitoring guidelines as ceiling or average values; (2) whether carcinogenic substances should be treated differently from agents with other toxic outcomes; (3) the method of accounting for variability among individual workers; and (4) the extent to which these guidelines should be extended to include genetic markers, indicators of susceptibility, or indicators of early biological response.

Report this publication

Statistics

Seen <100 times