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Analysis of 2-carbon-11-thymidine blood metabolites in PET imaging.

Authors
  • Shields, A F
  • Mankoff, D
  • Graham, M M
  • Zheng, M
  • Kozawa, S M
  • Link, J M
  • Krohn, K A
Type
Published Article
Journal
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Publication Date
Feb 01, 1996
Volume
37
Issue
2
Pages
290–296
Identifiers
PMID: 8667064
Source
Medline
License
Unknown

Abstract

While it is essential to take metabolites into account when interpreting results obtained with 11C-thymidine, the reproducibility of these degradation curves may allow the use of a limited number of samples to measure the catabolic products of thymidine. These data from the blood, along with tissue kinetic models, are needed to calculate DNA synthetic rates.

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