Affordable Access

deepdyve-link
Publisher Website

Amyloidosis: an unusual case of persistent oral ulceration.

Authors
  • Viggor, Sarah Francesca1
  • Frezzini, Cristina
  • Farthing, Paula M
  • Freeman, Christine O
  • Yeoman, Christine M
  • Thornhill, Martin H
  • 1 Department of Oral and Maxillofacial Medicine and Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK. [email protected]
Type
Published Article
Journal
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
Publication Date
Nov 01, 2009
Volume
108
Issue
5
Identifiers
DOI: 10.1016/j.tripleo.2009.06.031
PMID: 19773186
Source
Medline
Language
English
License
Unknown

Abstract

We report a case of systemic amyloidosis, with an unusual oral presentation, in a 70-year-old patient suffering from light chain myeloma. The patient presented with extensive ulceration of the tongue and alveolar ridges, and a large swelling in the floor of mouth. Incisional biopsies of the tongue and floor of mouth confirmed amyloid deposition within the tissues with evidence of necrotic ulceration. Amyloid deposition in the oral cavity usually manifests as macroglossia, however it can present elsewhere in the mouth as nodular or plaquelike lesions. Ulceration is a rare finding. This case highlights the variable nature of this condition, and how it can present a challenge to clinicians in terms of diagnosis and treatment.

Report this publication

Statistics

Seen <100 times