Comparative analysis of results of conservative treatment of pain syndrome after diskectomy was performed. Analyzed patients were divide into 2 groups (main and control). In the first group barotherapy was used along with the standard conservative treatment. Preliminary results of comparative analysis of 2 groups demonstrated significant advantages of this method. Excellent and good results dominated in the main group over control group with difference 8.9% (p = 0.046). Oxidative status of organism was studied to verify our results. We relied on changes in parameters of peroxide oxidation lipids--antioxidation system to indicate effectiveness of hyperbaric oxygenation. Calculation of quantitative index of inflammatory activity was suggested to predict results of surgical treatment. Finally, the authors made a conclusion that barotherapy combined with standard conservative treatment is effective and pathogenetically reasonable method for treating patients with recurrent radicular pain after microdiskectomy.