Affordable Access

Amphotericin B- and Fluconazole-Resistant Candida spp., Aspergillus fumigatus, and Other Newly Emerging Pathogenic Fungi Are Susceptible to Basic Antifungal Peptides

Authors
  • Eva J. Helmerhorst
  • Ingrid M. Reijnders
  • Wim van ’t Hof
  • Ina Simoons-Smit
  • Enno C. I. Veerman
  • Arie V. Nieuw Amerongen
Publisher
American Society for Microbiology
Publication Date
Mar 01, 1999
Source
PMC
Keywords
Disciplines
  • Design
License
Unknown

Abstract

The present study shows that a number of basic antifungal peptides, including human salivary histatin 5, a designed histatin analog designated dhvar4, and a peptide from frog skin, PGLa, are active against amphotericin B-resistant Candida albicans, Candida krusei, and Aspergillus fumigatus strains and against a fluconazole-resistant Candida glabrata isolate.

Report this publication

Statistics

Seen <100 times