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Amlodipine enhances amelioration of vascular insulin resistance, oxidative stress, and metabolic disorders by candesartan in metabolic syndrome rats.

Authors
  • 1
  • 1 Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan. , (Japan)
Type
Published Article
Journal
American Journal of Hypertension
1941-7225
Publisher
Oxford University Press
Publication Date
Volume
25
Issue
6
Pages
704–710
Identifiers
DOI: 10.1038/ajh.2012.26
PMID: 22421905
Source
Medline
License
Unknown

Abstract

ARB and CCB combination synergistically ameliorated vascular insulin resistance in metabolic syndrome, being associated with the synergistic attenuation of vascular oxidative stress and metabolic disorders.

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