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Ameloblastic carcinoma: Clinicopathological analysis of 18 cases and a systematic review.

Authors
  • Deng, Ling1, 2
  • Wang, Rui1
  • Yang, Mingzhong3
  • Li, Wei1
  • Zou, Ling4
  • 1 Nursing School, Guizhou University of Traditional Chinese Medicine, Guiyang, China. , (China)
  • 2 State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. , (China)
  • 3 State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu, China. , (China)
  • 4 State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China. , (China)
Type
Published Article
Journal
Head & neck
Publication Date
Dec 01, 2019
Volume
41
Issue
12
Pages
4191–4198
Identifiers
DOI: 10.1002/hed.25926
PMID: 31444935
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Exploring the clinicopathological features of ameloblastic carcinoma (AC) and reviewing the literature to improve the diagnosis and treatment of the disease. Clinical data and pathological features of 18 cases of AC were retrospectively analyzed. A systematic review was carried out by searching PubMed and Medline databases using the MeSH terms "ameloblastic" and "carcinoma." In the systematic analysis, 125 cases of AC from 81 eligible original studies and 18 cases of AC from this research were included. The male-to-female ratio was 2.58:1, and the mandible-to-maxilla ratio was 1.80:1. Mean age of patients was 45.3 years. Thirty-seven cases of recurrence and 27 cases of metastasis were recorded. AC is a rare neoplasm of the odontogenic epithelium. A systematic review indicates that diagnoses at the early phase and a close periodic assessment for recurrence and metastasis are necessary. © 2019 Wiley Periodicals, Inc.

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