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aMAGEing new players enter the RING to promote ubiquitylation.

Authors
Type
Published Article
Journal
Molecular Cell
Publisher
Elsevier
Volume
39
Issue
6
Pages
835–837
Identifiers
DOI: 10.1016/j.molcel.2010.09.006
Source
O'Shea Lab
License
Unknown

Abstract

The MAGE proteins are best known as curious tumor-specific antigens. However, Doyle et al. (2010) reveal that MAGE proteins interact with RING proteins to promote ubiquitylation which provides important new insights into the physiological and pathological functions of this enigmatic family of proteins.

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