An alternative synthesis of 4,4-dimethyl-5 alpha-cholesta-8,14,24-trien-3 beta-ol, an intermediate in sterol biosynthesis and a reported activator of meiosis and of nuclear orphan receptor LXR alpha.
- Published Article
Bioorganic & Medicinal Chemistry Letters
- Publication Date
Feb 03, 1998
4,4-dimethyl-5 alpha-cholesta-8,14,24-trien-3 beta-ol, a sterol of current biological interest, has been synthesized in six steps from 3 beta-acetoxy-4,4-dimethyl-5 alpha-cholest-8(14)-en-15-one.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/9871660