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[Alternative complement pathway].

Authors
  • Jouvin, M H
  • Kazatchkine, M
Type
Published Article
Journal
La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Publication Date
May 03, 1984
Volume
60
Issue
19
Pages
1371–1378
Identifiers
PMID: 6326330
Source
Medline
License
Unknown

Abstract

The alternative complement pathway comprises three component proteins C3, B, D and three regulatory proteins P, H and I. These plasma proteins represent the major humoral defense mechanism against infection in a non-immune host. The following topics are reviewed: biochemistry of the alternative pathway proteins; molecular mechanisms of activation and regulation of the pathway; involvement of the alternative pathway in human diseases.

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