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Altered growth and radiosensitivity in neural precursor cells subjected to oxidative stress.

Authors
Type
Published Article
Journal
International journal of radiation biology
Publication Date
Volume
82
Issue
9
Pages
640–647
Identifiers
PMID: 17050476
Source
Medline
License
Unknown

Abstract

Collectively our results provide further support for the importance of redox state in the regulation of neural precursor cell function, and suggest that oxidative stress can inhibit the proliferative potential of cells through different mechanisms. This is likely to compromise survival and under conditions where excess exogenous oxidants might predominate, sensitivity to irradiation may be enhanced.

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