Affordable Access

deepdyve-link
Publisher Website

Altered Global 5-Hydroxymethylation Status in Hidradenitis Suppurativa: Support for an Epigenetic Background.

Authors
  • Hessam, Schapoor1
  • Sand, Michael
  • Lang, Kerstin
  • Käfferlein, Heiko U
  • Scholl, Lisa
  • Gambichler, Thilo
  • Skrygan, Marina
  • Brüning, Thomas
  • Stockfleth, Eggert
  • Bechara, Falk G
  • 1 Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, Germany. , (Germany)
Type
Published Article
Journal
Dermatology
Publisher
S. Karger AG
Publication Date
Jan 01, 2017
Volume
233
Issue
2-3
Pages
129–135
Identifiers
DOI: 10.1159/000478043
PMID: 28750404
Source
Medline
Keywords
License
Unknown

Abstract

Our findings indicate that imbalances in DNA hydroxymethylation may play a role in the pathogenesis of HS rather than DNA methylation. Further studies are warranted to investigate the significance of DNA hydroxymethylation and the regulating enzymes in HS in order to advance our knowledge of the inflammatory network in this disease.

Report this publication

Statistics

Seen <100 times