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Alterations in expression of endometrial milk fat globule-EGF factor 8 (MFG-E8) and leukemia inhibitory factor (LIF) in patients with infertility and endometriosis.

Authors
  • Schmitz, Carla Regina1
  • Oehninger, Sergio2
  • Genro, Vanessa Krebs3
  • Chandra, Neelima2
  • Lattanzio, Frank4
  • Yu, Liang2
  • Cunha-Filho, João Sabino1, 3
  • 1 Graduate Program in Internal Medicine of the Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. , (Brazil)
  • 2 Department of Obstetrics and Gynecology, Eastern Virginia Medical School, The Jones Institute for Reproductive Medicine, Norfolk VA, USA.
  • 3 Department of Obstetrics and Gynecology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. , (Brazil)
  • 4 Department of Physiological Sciences, Eastern Virginia Medical School, Norfolk VA, USA.
Type
Published Article
Journal
JBRA assisted reproduction
Publication Date
Dec 01, 2017
Volume
21
Issue
4
Pages
313–320
Identifiers
DOI: 10.5935/1518-0557.20170056
PMID: 28967712
Source
Medline
Keywords
License
Unknown

Abstract

This study showed for the first time that MFG-E8 expression is impaired in the endometrium of patients with endometriosis and infertility during the window of implantation. Moreover, LIF is also diminished in the endometrium of these patients as shown before.

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