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Alpha-glucosidase inhibitory constituents from Cuscuta reflexa.

Authors
  • Anis, Erum
  • Anis, Itrat
  • Ahmed, Saeed
  • Mustafa, Ghulam
  • Malik, Abdul
  • Afza, Nighat
  • Hai, Syed Muhammad Abdul
  • Shahzad-ul-hussan, Syed
  • Choudhary, Muhammad Iqbal
Type
Published Article
Journal
Chemical and Pharmaceutical Bulletin
Publisher
Pharmaceutical Society of Japan
Publication Date
January 2002
Volume
50
Issue
1
Pages
112–114
Identifiers
PMID: 11824569
Source
Medline
License
Unknown

Abstract

Two new compounds, 7'-(3',4'-dihydroxyphenyl)-N-[(4-methoxyphenyl)ethyl]propenamide (4), and 7'-(4'-hydroxy,3'-methoxyphenyl)-N-[(4-butylphenyl)ethyl]propenamide (5) have been isolated from Cuscuta reflexa along with five known compounds, 6,7-dimethoxy-2H-1-benzopyran-2-one (1), 3-(3,4-dihydroxyphenyl)-2-propen-1-ethanoate (2), 6,7,8-trimethoxy-2H-1-benzopyran-2-one (3), 3-(4-O-beta-D-glucopyranoside-3,5-dimethoxyphenyl)-2-propen-1-ol (6), 2-(3-hydroxy-4-methoxyphenyl)-3,5-dihydroxy-7-O-beta-D-glucopyranoside-4H-1-benzopyrane-4-one (7), reported for the first time from this species. Structures of these compounds were determined by spectral analysis. These compounds showed strong inhibitory activity against alpha-glucosidase.

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