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Alleviation of behavioral hypersensitivity in mouse models of inflammatory pain with two structurally different casein kinase 1 (CK1) inhibitors.

Authors
  • Kurihara, Takashi
  • Sakurai, Eri
  • Toyomoto, Masayasu
  • Kii, Isao
  • Kawamoto, Daisuke
  • Asada, Toshihide
  • Tanabe, Tsutomu
  • Yoshimura, Megumu
  • Hagiwara, Masatoshi
  • Miyata, Atsuro
Type
Published Article
Journal
Molecular Pain
Publisher
SAGE Publications
Publication Date
Jan 01, 2014
Volume
10
Pages
17–17
Identifiers
DOI: 10.1186/1744-8069-10-17
PMID: 24612480
Source
Medline
License
Unknown

Abstract

These results suggest that CK1 plays an important pathophysiological role in spinal inflammatory pain transmission, and that inhibition of the CK1 activity may provide a novel strategy for the treatment of inflammatory pain.

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