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The agnogene of the human polyomavirus BK is expressed.

Authors
  • Rinaldo, C H
  • Traavik, T
  • Hey, A
Type
Published Article
Journal
Journal of virology
Publication Date
Jul 01, 1998
Volume
72
Issue
7
Pages
6233–6236
Identifiers
PMID: 9621096
Source
Medline
License
Unknown

Abstract

Primate polyomavirus genomes all contain an open reading frame at the 5' end of the late coding region called the agnogene. A simian virus 40 agnoprotein with unknown functions has previously been demonstrated. We now show that a BK virus agnoprotein appears in the perinuclear area and cytoplasm late in the infectious cycle. It is phosphorylated in vivo and coimmunoprecipitates with a subset of host cell proteins.

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