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Agent Orange toxicity: a quantitative perspective.

Authors
  • Stevens, K M
Type
Published Article
Journal
Human toxicology
Publication Date
Jan 01, 1981
Volume
1
Issue
1
Pages
31–39
Identifiers
PMID: 7348691
Source
Medline
License
Unknown

Abstract

1 The minimum toxic dose of tetrachloro-dibenzo-p-dioxin (TCDD) for man has been calculated from monkey and human data to be 0.1 microgram kg-1. 2 The amount of TCDD which man takes in from his environment is about 1/2050 of that present in one square metre of his immediate environment. 3 The average concentration of TCDD present in Vietnam immediately after spraying Agent Orange was 8 microgram m-2. 4 A soldier directly sprayed would attain an internal body concentration of 7 X 10(-5) microgram kg-1 or 1/1750 of the minimum toxic dose; soldiers moving through previously sprayed areas would ingest much less. 5 These quantitative aspects indicate that the dioxin sprayed with Agent Orange in Vietnam cannot have caused systemic illnesses in Vietnam veterans or birth defects in their children.

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