Age-related total gray matter and white matter changes in normal adult brain. Part I: volumetric MR imaging analysis.
- Published Article
AJNR. American journal of neuroradiology
- Publication Date
Sep 01, 2002
GM volume loss appears to be a constant, linear function of age throughout adult life, whereas WM volume loss seems to be delayed until middle adult life. Both appear to be independent of sex. Quantitative analysis of %GM and %WM volumes can improve our understanding of brain atrophy due to normal aging; this knowledge may be valuable in distinguishing atrophy of disease patterns from characteristics of the normal aging process.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/12223373