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Age-related nuclear size variability of thyreocytes in thyroid aspirates.

Authors
  • Feichter, G E
  • Goerttler, K
Type
Published Article
Journal
Analytical and quantitative cytology
Publication Date
Jun 01, 1983
Volume
5
Issue
2
Pages
75–78
Identifiers
PMID: 6881765
Source
Medline
License
Unknown

Abstract

Variations in nuclear areas in thyroid aspirates may be caused by many different pathologic conditions of the thyroid gland. Our experience in routine thyroid cytology has suggested that the age of the patient could also be a factor that can influence the nuclear size of thyroid epithelial cells. Planimetric measurements of nuclear areas of cytologically normal thyroid nuclei from patients with normal thyroid glands and from those with cold thyroid nodules, with each category containing two different age groups, revealed both a significant increase in nuclear areas in normal thyroid tissue from older patients and a significant increase in nuclear size variability among older patients with nodular goiters. This finding seems to indicate that patient age is another factor that exercises an influence upon the variability of nuclear areas, even in histologically normal thyroid glands.

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