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Age-related changes in the beagle spine.

Authors
Type
Published Article
Journal
Acta Orthopaedica Scandinavica
0001-6470
Publisher
Informa UK (Taylor & Francis)
Publication Date
Volume
59
Issue
5
Pages
503–507
Identifiers
PMID: 3188853
Source
Medline

Abstract

Age-related changes were evaluated in the spines of beagle dogs by radiology, histology, and mechanical testing. Thirty healthy beagle dogs were divided into five groups having mean ages of 2-14 years. Radiographs were taken of intact spines at the time of death and of defleshed spines at necropsy. Cervical, thoracic, and lumbar segments were tested in compression to calculate peak stress, peak strain, and elastic modulus. Adjacent spine segments were graded grossly for osteophyte development, and sections of the intervertebral discs were evaluated histologically. Histologic evidence of disc degeneration and changes in the mechanical properties of the intervertebral disc joint preceded radiographic changes. Changes in the mechanical properties of the disc space were probably a result of the disc degeneration rather than the spondylitic lesions.

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