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Study of a newly developed high-performance liquid chromatography analyser for glycosylated haemoglobin measurements in blood containing haemoglobin variants in the Japanese population.

Authors
  • Miyashita, Tetsuo1
  • Sugiyama, Takahiro1
  • Yamadate, Shuukoh2
  • Nagashima, Masaaki3
  • Satomura, Atsushi3
  • Nakayama, Tomohiro4
  • 1 Department of Clinical Laboratory, Nihon University Itabashi Hospital, Tokyo, Japan. , (Japan)
  • 2 Department of Clinical Laboratory, Nihon University Itabashi Hospital, Tokyo, Japan Division of Laboratory Medicine, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan. , (Japan)
  • 3 Division of Laboratory Medicine, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan. , (Japan)
  • 4 Department of Clinical Laboratory, Nihon University Itabashi Hospital, Tokyo, Japan Division of Laboratory Medicine, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo, Japan [email protected] , (Japan)
Type
Published Article
Journal
Annals of Clinical Biochemistry International Journal of Laboratory Medicine
Publisher
SAGE Publications
Publication Date
Sep 01, 2014
Volume
51
Issue
Pt 5
Pages
591–601
Identifiers
DOI: 10.1177/0004563213513244
PMID: 24399366
Source
Medline
Keywords
License
Unknown

Abstract

GX is useful for the analysis of HbA1c samples that contain HbD, HbS, HbC and haemoglobin variants, even though the elution times are similar. However, a countermeasure is needed in order to avoid overlooking other haemoglobin variants in Japan.

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